Institute of Molecular Genetics of the Czech Academy of Sciences
The IMG Directors’ Award is granted to the team of authors of an original publication that appeared in the past calendar year. Every year, three best publications shall be awarded. The Award is announced and granted by the Director of IMG on the basis of proposals by the IMG Council.
The funds associated with granting the Award are covered from the estate of former IMG Director, prof. Josef Říman, MD, DSc, whose wish was “to use these funds for awarding individuals and / or scientific teams for novel essential scientific knowledge obtained in scientific research every calendar year”.
| 1 | Vanickova K, Milosevic M, Ribeiro Bas I, Burocziova M, Yokota A, Danek P, Grusanovic S, Chiliński M, Plewczynski D, Rohlena J, Hirai H, Rohlenova K, Alberich-Jorda M: Hematopoietic stem cells undergo a lymphoid to myeloid switch in early stages of emergency granulopoiesis. EMBO J 2023 42(23): e113527. [pubmed] [doi] |
| 2nd position | Storchova R, Palek M, Palkova N, Veverka P, Brom T, Hofr C, Macurek L: Phosphorylation of TRF2 promotes its interaction with TIN2 and regulates DNA damage response at telomeres. Nucleic Acids Res 2023 51(3): 1154-1172. [pubmed] [doi] |
| 3rd position | Pánek J, Roithová A, Radivojević N, Sýkora M, Prusty AB, Huston N, Wan H, Pyle AM, Fischer U, Staněk D: The SMN complex drives structural changes in human snRNAs to enable snRNP assembly. Nat Commun 2023 14(1): 6580. [pubmed] [doi] |
(Authors from IMG are underlined)
| 1 | Horkova V, Drobek A, Paprckova D, Niederlova V, Prasai A, Uleri V, Glatzova D, Kraller M, Cesnekova M, Janusova S, Salyova E, Tsyklauri O, Kadlecek TA, Krizova K, Platzer R, Schober K, Busch DH, Weiss A, Huppa JB, Stepanek O: Unique roles of co-receptor-bound LCK in helper and cytotoxic T cells. Nat Immunol 2023 24(1): 174-185. (Epub 2022 Dec 23.) [pubmed] [doi] |
| 2nd position | Zapletal D, Taborska E, Pasulka J, Malik R, Kubicek K, Zanova M, Much C, Sebesta M, Buccheri V, Horvat F, Jenickova I, Prochazkova M, Prochazka J, Pinkas M, Novacek J, Joseph DF, Sedlacek R, Bernecky C, O’Carroll D, Stefl R, Svoboda P: Structural and functional basis of mammalian microRNA biogenesis by Dicer. Mol Cell 2022 82(21): 4064-4079.e13. [pubmed] [doi] |
| 3rd position | Cihlarova Z, Kubovciak J, Sobol M, Krejcikova K, Sachova J, Kolar M, Stanek D, Barinka C, Yoon G, Caldecott KW, Hanzlikova H: BRAT1 links Integrator and defective RNA processing with neurodegeneration. Nat Commun 2022 13(1): 5026. [pubmed] [doi] |
(Authors from IMG are underlined)
| 1 | Loubalova Z, Fulka H, Horvat F, Pasulka J, Malik R, Hirose M, Ogura A, Svoboda P: Formation of spermatogonia and fertile oocytes in golden hamsters requires piRNAs. Nat Cell Biol 2021 23(9): 992-1001. [pubmed] [doi] |
| 2nd position | Dupacova N, Antosova B, Paces J, Kozmik Z: Meis homeobox genes control progenitor competence in the retina. Proc Natl Acad Sci U S A 2021 118(12). [pubmed] [doi] |
| 3rd position | Klimešová K, Vojáčková J, Radivojević N, Vandermoere F, Bertrand E, Verheggen C, Staněk D: TSSC4 is a component of U5 snRNP that promotes tri-snRNP formation. Nat Commun 2021 12(1): 3646. [pubmed] [doi] |
(Authors from IMG are underlined)
| 1st position | Vobořil M, Brabec T, Dobeš J, Šplíchalová I, Březina J, Čepková A, Dobešová M, Aidarova A, Kubovčiak J, Tsyklauri O, Štěpánek O, Beneš V, Sedláček R, Klein L, Kolář M, Filipp D: Toll-like receptor signaling in thymic epithelium controls monocyte-derived dendritic cell recruitment and Treg generation. Nat Commun 2020 11(1): 2361. [pubmed] [doi] |
| 2nd position | Koslová A, Trefil P, Mucksová J, Reinišová M, Plachý J, Kalina J, Kučerová D, Geryk J, Krchlíková V, Lejčková B, Hejnar J: Precise CRISPR/Cas9 editing of the NHE1 gene renders chickens resistant to the J subgroup of avian leukosis virus. Proc Natl Acad Sci U S A 2020 117(4): 2108-2112. [pubmed] [doi] |
| 3rd position (shared) | Danek P, Kardosova M, Janeckova L, Karkoulia E, Vanickova K, Fabisik M, Lozano Asencio C, Benoukraf T, Tirado-Magallanes R, Zhou Q, Burocziova M, Rahmatova S, Pytlik R, Brdicka T, Tenen DG, Korinek V, Alberich Jorda M: β-catenin-TCF/LEF signaling promotes steady-state and emergency granulopoiesis via G-CSF receptor upregulation. Blood 2020 136(22): 2574-2587. [pubmed] [doi] Hanzlikova H, Prokhorova E, Krejcikova K, Cihlarova Z, Kalasova I, Kubovciak J, Sachova J, Hailstone R, Brazina J, Ghosh S, Cirak S, Gleeson JG, Ahel I, Caldecott KW: Pathogenic ARH3 mutations result in ADP-ribose chromatin scars during DNA strand break repair. Nat Commun 2020 11(1): 3391. [pubmed] [doi] |
(Authors from IMG are underlined)
| 1st position | Balounová J, Šplíchalová I, Dobešová M, Kolář M, Fišer K, Procházka J, Sedlacek R, Jurisicova A, Sung HK, Kořínek V, Alberich-Jorda M, Godin I, Filipp D: Toll-like receptor 2 expression on c-kit cells tracks the emergence of embryonic definitive hematopoietic progenitors. Nat Commun 2019 10(1): 5176. [pubmed] [doi] |
| 2nd position | Krchnáková Z, Thakur PK, Krausová M, Bieberstein N, Haberman N, MüllerMcNicoll M, Stanek D: Splicing of long non-coding RNAs primarily depends on polypyrimidine tract and 5′ splice-site sequences due to weak interactions with SR proteins. Nucleic Acids Res 2019 47(2): 911-928. [pubmed] [doi] [Open access] |
| 3rd position | Mihola O, Pratto F, Brick K, Linhartova E, Kobets T, Flachs P, Baker CL, Sedlacek R, Paigen K, Petkov PM, Camerini-Otero RD, Trachtulec Z: Histone methyltransferase PRDM9 is not essential for meiosis in male mice. Genome Res 2019 29(7): 1078-1086. [pubmed] [doi] |
(Authors from IMG are underlined)
| 1st position | Hanzlikova H, Kalasova I, Demin AA, Pennicott LE, Cihlarova Z, Caldecott KW: The Importance of Poly(ADP-Ribose) Polymerase as a Sensor of Unligated Okazaki Fragments during DNA Replication. Mol Cell 2018 71(2): 319-331.e3. [pubmed] [doi] |
| 2nd position | Jirouskova M, Nepomucka K, Oyman-Eyrilmez G, Kalendova A, Havelkova H, Sarnova L, Chalupsky K, Schuster B, Benada O, Miksatkova P, Kuchar M, Fabian O, Sedlacek R, Wiche G, Gregor M: Plectin controls biliary tree architecture and stability in cholestasis. J Hepatol 2018 68(5): 1006-1017. [pubmed] [doi] |
| 3rd position | Drobek A, Moudra A, Mueller D, Huranova M, Horkova V, Pribikova M, Ivanek R, Oberle S, Zehn D, McCoy KD, Draber P, Stepanek O: Strong homeostatic TCR signals induce formation of self-tolerant virtual memory CD8 T cells. EMBO J 2018 37(14). [pubmed] [doi] |
(Authors from IMG are underlined)
| 1st position | Skuta C, Popr M, Muller T, Jindrich J, Kahle M, Sedlak D, Svozil D, Bartunek P: Probes & Drugs Portal: an interactive, open data resource for chemical biology. Nat Methods. 2017 14(8): 759-760. [pubmed] [doi] |
| 2nd position | Lounková A, Kosla J, Přikryl D, Štafl K, Kučerová D, Svoboda J: Retroviral host range extension is coupled with Env-activating mutations resulting in receptor-independent entry. Proc Natl Acad Sci U S A 2017 114(26): E5148-E5157. [pubmed] [doi] |
(Authors from IMG are underlined)
