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Institute of Molecular Genetics of the Czech Academy of Sciences
Institute of Molecular Genetics of the Czech Academy of Sciences

Lecture – Dr. Jens Volker

  • Date & Time: 25. 6. 2013  |  15:00
  • Location: IMG, Lecture room 0.195

Jens is an expert on thermodynamics of DNA, especially of its unusual forms.

“Energy Landscapes of Stable and Metastable DNA States Implicated in Repeat DNA Expansion and Disease States”

 

Dr. Jens Volker

Department of Chemistry and Chemical Biology Rutgers, The State University of New Jersey
Jens is an expert on thermodynamics of DNA, especially of its unusual forms.

 

References e.g.:

  • Völker J, Gindikin V, Klump HH, Plum GE, Breslauer KJ:
    Energy landscapes of dynamic ensembles of rolling triplet repeat bulge loops: implications for DNA expansion associated with disease states. J. Am. Chem. Soc. (2012) 134: 6033-44. [doi]
  • Völker J, Plum GE, Klump HH, Breslauer KJ:
    Energy crosstalk between DNA lesions: implications for allosteric coupling of DNA repair and triplet repeat expansion pathways. J. Am. Chem. Soc. (2010) 132: 4095-7. [doi]
  • Völker J, Klump HH, Breslauer KJ:
    DNA energy landscapes via calorimetric detection of microstate ensembles of metastable macrostates and triplet repeat diseases. Proc. Natl. Acad. Sci. USA (2008) 105: 18326-30. [doi] 

 

Host: Dr. Bohdan Schneider, Institute of Biotechnology AS CR